產(chǎn)品:牛腦垂體提取物
貨號:0703
Product Description
The pituitary gland is a small endocrine gland which produces and secretes various hormones vital to the regulation of various bodily functions. Hormones secreted by the pituitary stimulate and control the functioning of almost all other endocrine glands as well as the growth and water balance of the body. In vitro studies demonstrate that bovine pituitary extract (BPE) promote epithelial cell, endothelial cell and melanocyte proliferation [1, 2, 3]. BPE has been widely used as an additional supplement in the culture of various epithelial cells and melanocytes.
BPE from ScienCell Research Laboratories is obtained from the extraction of fresh frozen bovine pituitary glands in saline solution. The pituitaries are collected in the contiguous 48 United States only from USDA inspected facilities where animals receive ante and post mortem inspection. The pituitaries are found free of contagious diseases. The product is sterile filtered and kept at -20°C.
Product Use
BPE is for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.
Storage Store the BPE at -20°C until ready for use. Repeated freeze-thaws will reduce activity and should be avoided by proper aliquoting.
Shipping Dry ice.
Reference
[1] Abdel-Naser MB. (2003) Mitogen requirements of normal epidermal human melanocytes in a serum and tumor promoter free medium. Eur J Dermatol. 13(1):29-33.
[2] Maciag, T., Cerundolo, S., Ilseley, P.R., and Forand, R. (1979) An endothelial cell growth factor from bovine hypothalamus: Identification and partial characterization. Proc Natl Acad Sci. 76(11):5674-8.
[3] Tsao, M.C., Walthall, B.J., and Ham, R.G. (1982) Clonal growth of normal human epidermal keratinocytes in a defined medium. J Cell Physiol. 110(2):219-29.
關(guān)鍵詞:
牛腦垂體提取物
復蒙基因|FMGBio(www.fmgbio.com/ www.sciencell-sh.com/ )成立于2005年, 是專業(yè)從事牛血清生產(chǎn)、銷售高端的原代細胞類科研產(chǎn)品。這些產(chǎn)品從根本上提高了全球生命醫(yī)學研究、人類重要疾病藥物研發(fā)、新藥研發(fā)的成功率。近幾年的新藥研發(fā)成功率在逐年下降,其根本原因之一就是傳統(tǒng)的藥物篩選系統(tǒng)是建立在只具有30-40%人類基因群的一系列細胞株上。這樣一個有“缺陷型”藥物篩選系統(tǒng)所產(chǎn)生的藥物用于人體上就會出現(xiàn)許多致命的弱點和不完整性。新一代藥物篩選系統(tǒng)是含有一系列近乎完整的人類基因群的原代細胞株。而利用這些原代細胞株所甄別和篩選出來的候選藥物,其診治人類疾病的成功幾率將大大增加。這樣不但大大節(jié)省了新藥的開發(fā)成本,而且將極大地提高人類的健康質(zhì)量。
復蒙基因|FMGBio現(xiàn)有的產(chǎn)品:美國Sciencell(原代細胞、原代細胞專用培養(yǎng)基、無血清培養(yǎng)基)、3D Bioteck(三維細胞培養(yǎng)支架)、年產(chǎn)1000萬毫升的內(nèi)蒙古牛血清生產(chǎn)基地等。
復蒙基因|FMGBio的PI團隊已經(jīng)發(fā)展到專職PI 20人,聯(lián)席PI 312人,其中大多數(shù)擁有海外背景。截止到2009年3月,以PI或聯(lián)席PI為第一作者發(fā)表SCI 論文1682 篇(總IF 值為5721.82,其中影響因子IF>5.0 的論文216 篇,IF>10.0論文32 篇)。